FBW7 targets KLF10 for ubiquitin-dependent degradation

Yu, S; Wang, F; Tan, X; Gao, GL; Pan, WJ; Luan, Y; Ge, X

Ge, X (reprint author), Tongji Univ, Dept Clin Med, Shanghai Peoples Hosp 10, Sch Med, Shanghai 200072, Peoples R China.; Luan, Y (reprint author), Tongji Univ, Dept Cent Lab, Shanghai Peoples Hosp 10, Sch Med, Shanghai 200072, Peoples R China.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018; 495 (2): 2092

Abstract

FBW7, a key component of SCFFBw7 E3 ubiquitin ligase, targets various proteins for degradation via the conserved Cdc4 phosphodegron (CPD) in substrate......

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