Deficiency of Caspase-1 Attenuates HIV-1-Associated Atherogenesis in Mice

Alam, MA; Caocci, M; Ren, M; Chen, Z; Liu, FM; Khatun, MS; Kolls, JK; Qin, XB; Burdo, TH

Qin, XB (通讯作者)，Tulane Univ, Dept Comparat Pathol, Tulane Natl Primate Res Ctr, Sch Med, 18703 Three Rivers Rd, Covington, LA 70433 USA.;Qin, XB (通讯作者)，Tulane Univ, Sch Med, Dept Microbiol & Immunol, New Orleans, LA 70112 USA.;Burdo, TH (通讯作者)，Temple Univ, Dept Microbiol Immunol & Inflammat, Ctr NeuroVirol & Gene Editing, Lewis Katz Sch Med, Philadelphia, PA 19140 USA.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (16):

Abstract

Within arterial plaque, HIV infection creates a state of inflammation and immune activation, triggering NLRP3/caspase-1 inflammasome, tissue damage, a......

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