Targeting ASGR1 to lower cholesterol

Rader, DJ

Rader, DJ (通讯作者)，Univ Penn, Perelman Sch Med, Dept Genet, Philadelphia, PA 19104 USA.;Rader, DJ (通讯作者)，Univ Penn, Perelman Sch Med, Dept Med, Philadelphia, PA 19104 USA.;Rader, DJ (通讯作者)，Univ Penn, Perelman Sch Med, Inst Translat Med & Therapeut, Philadelphia, PA 19104 USA.;Rader, DJ (通讯作者)，Univ Penn, Perelman Sch Med, Inst Diabet Obes & Metab, Philadelphia, PA 19104 USA.;Rader, DJ (通讯作者)，Univ Penn, Perelman Sch Med, Cardiovasc Inst, Philadelphia, PA 19104 USA.

NATURE METABOLISM, 2022; 4 (8): 967

Abstract

New research reports that targeting the asialoglycoprotein receptor (ASGR1) in mice promotes cholesterol excretion through a mechanism involving stabi......

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