A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption

Zhang, YY; Fu, ZY; Wei, J; Qi, W; Baituola, G; Luo, J; Meng, YJ; Guo, SY; Yin, HY; Jiang, SY; Li, YF; Miao, HH; Liu, Y; Wang, Y; Li, BL; Ma, YT; Song, BL

Song, BL (reprint author), Wuhan Univ, Inst Adv Studies, Coll Life Sci, Hubei Key Lab Cell Homeostasis, Wuhan 430072, Hubei, Peoples R China.; Ma, YT (reprint author), Xinjiang Med Univ, State Key Lab Pathogenesis Prevent & Treatment Hi, Heart Ctr, Affili

SCIENCE, 2018; 360 (6393): 1087

Abstract

A high concentration of low-density lipoprotein cholesterol (LDL-C) is a major risk factor for cardiovascular disease. Although LDL-C levels vary amon......

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