Combined HMG-COA reductase and prenylation inhibition in treatment of CCM

Nishimura, S; Mishra-Gorur, K; Park, J; Surovtseva, YV; Sebti, SM; Levchenko, A; Louvi, A; Gunel, M

Louvi, A; Gunel, M (reprint author), Yale Sch Med, Dept Neurosurg, New Haven, CT 06520 USA.; Louvi, A; Gunel, M (reprint author), Yale Sch Med, Dept Neurosci, Program Neurogenet, New Haven, CT 06520 USA.; Gunel, M (reprint author), Yale Sch Med, Dept Gene

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017; 114 (21): 5503

Abstract

Cerebral cavernous malformations (CCMs) are common vascular anomalies that develop in the central nervous system and, more rarely, the retina. The les......

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