Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons

Liu, EY; Russ, J; Cali, CP; Phan, JM; Amlie-Wolf, A; Lee, EB

Lee, EB (reprint author), Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Translat Neuropathol Res Lab, Philadelphia, PA 19104 USA.

CELL REPORTS, 2019; 27 (5): 1409

Abstract

Loss of the nuclear RNA binding protein TAR DNA binding protein-43 (TDP-43) into cytoplasmic aggregates is the strongest correlate to neurodegeneratio......

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