HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway

Li, BY; Peng, WQ; Liu, Y; Guo, L; Tang, QQ

Tang, QQ (通讯作者)，Fudan Univ, Zhongshan Hosp, Sch Basic Med Sci, Dept Biochem & Mol Biol,Key Lab Metab & Mol Med,Mi, Shanghai 200032, Peoples R China.;Tang, QQ (通讯作者)，Fudan Univ, Zhongshan Hosp, Dept Endocrinol & Metab, Shanghai 200032, Peoples R China.;Guo, L (通讯作者)，Shanghai Univ Sport, Sch Exercise & Hlth, Shanghai 200438, Peoples R China.;Guo, L (通讯作者)，Shanghai Univ Sport, Shanghai Frontiers Sci Res Base Exercise & Metab H, Shanghai 200438, Peoples R China.

CELL REPORTS, 2023; 42 (7):

Abstract

Energy-dissipating adipocytes have the potential to improve metabolic health. Here, we identify hypoxiainduced gene domain protein-1a (HIGD1A), a mito......

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