Empagliflozin activates Wnt/beta-catenin to stimulate FUNDC1-dependent mitochondrial quality surveillance against type-3 cardiorenal syndrome

Cai, C; Wu, F; Zhuang, BJ; Ou, Q; Peng, XJ; Shi, NX; Peng, L; Li, ZY; Wang, J; Cai, SM; Tan, Y

Cai, SM; Tan, Y (通讯作者)，Southern Med Univ, Nanfang Hosp, Dept Crit Care Med, Guangzhou 510515, Peoples R China.;Wang, J (通讯作者)，Peking Univ, Dept Vasc Med, Shougang Hosp, Beijing 100144, Peoples R China.

MOLECULAR METABOLISM, 2022; 64 ():

Abstract

Objectives: Cardiorenal syndrome type-3 (CRS-3) is an abrupt worsening of cardiac function secondary to acute kidney injury. Mitochondrial dysfunction......

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