The UCP2-related mitochondrial pathway participates in rhein-induced apoptosis in HK-2 cells

Mao, Y; Zhang, MC; Yang, JP; Sun, H; Wang, DD; Zhang, XX; Yu, F; Li, J

Yu, F; Li, J (reprint author), China Pharmaceut Univ, Sch Basic Med & Clin Pharm, Dept Clin Pharm, Nanjing 211198, Jiangsu, Peoples R China.; Yu, F (reprint author), China Pharmaceut Univ, Key Lab Drug Qual Control & Pharmacovigilance, Minist Educ, Nanjin

TOXICOLOGY RESEARCH, 2017; 6 (3): 297

Abstract

Rhein is one of the main active compounds in total rhubarb anthraquinones (TRAs) that were reported to cause nephrotoxicity. This paper explored the m......

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