BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation

Zong, DL; Adam, S; Wang, YF; Sasanuma, H; Callen, E; Murga, M; Day, A; Kruhlak, MJ; Wong, N; Munro, M; Chaudhuri, AR; Karim, B; Xia, B; Takeda, S; Johnson, N; Durocher, D; Nussenzweig, A

Nussenzweig, A (reprint author), NCI, Lab Genome Integr, NIH, Bethesda, MD 20892 USA.

MOLECULAR CELL, 2019; 73 (6): 1267

Abstract

BRCA1 functions at two distinct steps during homologous recombination (HR). Initially, it promotes DNA end resection, and subsequently it recruits the......

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