Isoform-resolved transcriptome of the human preimplantation embryo

Torre, D; Francoeur, NJ; Kalma, Y; Carmel, IG; Melo, BS; Deikus, G; Allette, K; Flohr, R; Fridrikh, M; Vlachos, K; Madrid, K; Shah, H; Wang, YC; Sridhar, SH; Smith, ML; Eliyahu, E; Azem, F; Amir, H; Mayshar, Y; Marazzi, I; Guccione, E; Schadt, E; Ben-Yosef, D; Sebra, R

Sebra, R (通讯作者),Icahn Sch Med Mt Sinai, Dept Genet & Genom Sci, New York, NY 10029 USA.;Ben-Yosef, D (通讯作者),Tel Aviv Univ, Tel Aviv Sourasky Med Ctr, Fertil & IVF Inst, IL-64239 Tel Aviv, Israel.;Sebra, R (通讯作者),Icahn Sch Med Mt Sinai, Ctr Adv Genom Technol, New York, NY 10029 USA.;Sebra, R (通讯作者),Icahn Sch Med Mt Sinai, Icahn Genom Inst, New York, NY 10029 USA.;Ben-Yosef, D (通讯作者),Tel Aviv Univ, Sackler Fac Med, Sagol Sch Neurosci, Dept Cell & Dev Biol, Tel Aviv, Israel.;Ben-Yosef, D (通讯作者),Tel Aviv Sourasky Med Ctr, CORAL Ctr Regenerat & Longev, IL-64239 Tel Aviv, Israel.;Sebra, R (通讯作者),Icahn Sch Med Mt Sinai, Black Family Stem Cell Inst, New York, NY 10029 USA.

NATURE COMMUNICATIONS, 2023; 14 (1):

Abstract

Human preimplantation development involves extensive remodeling of RNA expression and splicing. However, its transcriptome has been compiled using sho......

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