Selective BET inhibitor RVX-208 ameliorates periodontal inflammation and bone loss

Sun, MX; Clayton, N; Alam, S; Asmussen, N; Wong, AD; Kim, JH; Luong, G; Mokhtari, S; Pellei, D; Carrico, CK; Schwartz, Z; Boyan, BD; Giannobile, WV; Sahingur, SE; Lin, Z

Lin, Z (通讯作者)，VCU Sch Dent, Dept Periodont, 521 North 11th St, Richmond, VA 23298 USA.

JOURNAL OF CLINICAL PERIODONTOLOGY, 2023; 50 (12): 1658

Abstract

Aim: To determine the effects of RVX-208, a selective bromodomain and extra-terminal domain (BET) inhibitor targeting bromodomain 2 (BD2), on periodon......

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