The Epithelial-Mesenchymal Transcription Factor SNAI1 Represses Transcription of the Tumor Suppressor miRNA let-7 in Cancer

Wang, HM; Chirshev, E; Hojo, N; Suzuki, T; Bertucci, A; Pierce, M; Perry, C; Wang, RN; Zink, J; Glackin, CA; Ioffe, YJ; Unternaehrer, JJ

Unternaehrer, JJ (corresponding author), Loma Linda Univ, Dept Basic Sci, Div Biochem, Loma Linda, CA 92354 USA.; Unternaehrer, JJ (corresponding author), Loma Linda Univ, Ctr Hlth Dispar & Mol Med, Loma Linda, CA 92354 USA.

CANCERS, 2021; 13 (6):

Abstract

Simple Summary When cells undergo epithelial-mesenchymal transition (EMT) they gain characteristics of stem cells. We investigated the mechanism by wh......

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