Rational design of microRNA-responsive switch for programmable translational control in mammalian cells

Ning, H; Liu, G; Li, L; Liu, Q; Huang, HY; Xie, Z

Xie, Z (通讯作者),Tsinghua Univ, Ctr Synthet & Syst Biol, MOE Key Lab Bioinformat, Dept Automat,Beijing Natl Res Ctr Informat Sci & T, Beijing 100084, Peoples R China.;Xie, Z (通讯作者),Tsinghua Univ, Ctr Synthet & Syst Biol, Bioinformat Div, Dept Automat,Beijing Natl Res Ctr Informat Sci & T, Beijing 100084, Peoples R China.

NATURE COMMUNICATIONS, 2023; 14 (1):

Abstract

Artificial RNA translation modulation usually relies on multiple components, such as RNA binding proteins (RBPs) or microRNAs (miRNAs) for off-switche......

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