CRISPR/Cas9 as an antiviral against Orthopoxviruses using an AAV vector

Siegrist, CM; Kinahan, SM; Settecerri, T; Greene, AC; Santarpia, JL

Siegrist, CM (corresponding author), Sandia Natl Labs, WMD Threats & Aerosol Sci, POB 5800, Albuquerque, NM 87185 USA.; Siegrist, CM (corresponding author), Univ Nebraska Med Ctr, Omaha, ND 68198 USA.

SCIENTIFIC REPORTS, 2020; 10 (1):

Abstract

A vaccine for smallpox is no longer administered to the general public, and there is no proven, safe treatment specific to poxvirus infections, leavin......

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