Fc-independent functions of anti-CTLA-4 antibodies contribute to anti-tumor efficacy

Sato, Y; Casson, CN; Matsuda, A; Kim, JI; Shi, JQ; Iwasaki, S; Chen, SS; Modrell, B; Chan, C; Tavares, D; Austen, D; Ida, K; Tayber, O; Hein, P; Comeau, R; Lin, YF; Shaw, MH

Shaw, MH (通讯作者)，Takeda Pharmaceut Int Co, Cambridge, MA 02139 USA.

CANCER IMMUNOLOGY IMMUNOTHERAPY, 2022; 71 (10): 2421

Abstract

Ipilimumab, a monoclonal antibody that recognizes cytotoxic T-lymphocyte associated protein 4 (CTLA-4), was the first immune checkpoint inhibitor appr......

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