Differential expression of hsa-miR-221, hsa-miR-21, hsa-miR-135b, and hsa-miR-29c suggests a field effect in oral cancer

Lopes, CB; Magalhaes, LL; Teofilo, CR; Alves, APNN; Montenegro, RC; Negrini, M; Ribeiro-dos-Santos, A

Ribeiro-dos-Santos, A (reprint author), Fed Univ Para, Grad Program Genet & Mol Biol, Lab Human & Med Genet, BR-66075110 Belem, Para, Brazil.; Ribeiro-dos-Santos, A (reprint author), Fed Univ Para, Res Ctr Oncol, BR-073005 Belem, PA, Brazil.

BMC CANCER, 2018; 18 ():

Abstract

Background: The theory of field effect suggests that the tumor-adjacent area, besides histopathologically normal, undergoes genetic and epigenetic cha......

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