Novel Crizotinib-GnRH Conjugates Revealed the Significance of Lysosomal Trapping in GnRH-Based Drug Delivery Systems

Muranyi, J; Varga, A; Gyulavari, P; Penzes, K; Nemeth, CE; Csala, M; Petho, L; Csampai, A; Halmos, G; Petak, I; Valyi-Nagy, I

Muranyi, J (reprint author), MTA SE Pathobiochem Res Grp, Tuzolto St 37-47, H-1094 Budapest, Hungary.; Muranyi, J (reprint author), Semmelweis Univ, Dept Med Chem Mol Biol & Pathobiochem, H-1094 Budapest, Hungary.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019; 20 (22):

Abstract

Several promising anti-cancer drug-GnRH (gonadotropin-releasing hormone) conjugates have been developed in the last two decades, although none of them......

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