High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans

Lima, RDL; Kongstad, KT; Kato, L; das Silva, MJ; Franzyk, H; Staerk, D

Staerk, D (reprint author), Univ Copenhagen, Fac Hlth & Med Sci, Dept Drug Design & Pharmacol, Univ Pk 2, DK-2100 Copenhagen, Denmark.

MOLECULES, 2018; 23 (7):

Abstract

Protein tyrosine phosphatase 1B (PTP1B) is an intracellular enzyme responsible for deactivation of the insulin receptor, and consequently acts as a ne......

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