MiR-15a/16-1 deficiency induces IL-10-producing CD19(+) TIM-1(+) cells in tumor microenvironment

Jia, XQ; Liu, H; Xu, C; Han, S; Shen, YT; Miao, X; Hu, XY; Lin, ZJ; Qian, L; Wang, ZB; Gong, WJ

Gong, WJ (reprint author), Yangzhou Univ, Inst Translat Med, Dept Basic Med, Med Coll, Yangzhou, Jiangsu, Peoples R China.; Wang, ZB (reprint author), Yangzhou Univ, Subei Peoples Hosp Jiangsu Prov, Dept Gen Surg, Yangzhou, Jiangsu, Peoples R China.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019; 23 (2): 1343

Abstract

IL-10-producing B cells (B10) are associated with autoimmune diseases, infection and tumours. MiR-15a/16 as a tumour-suppressive gene is down-regulate......

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