TEAD Inhibitors Sensitize KRASG12C Inhibitors via Dual Cell Cycle Arrest in KRASG12C-Mutant NSCLC

Tammaccaro, SL; Prigent, P; Le Bail, JC; Dos-Santos, O; Dassencourt, L; Eskandar, M; Buzy, A; Venier, O; Guillemot, JC; Veeranagouda, Y; Didier, M; Spanakis, E; Kanno, T; Cesaroni, M; Mathieu, S; Canard, L; Casse, A; Windenberger, F; Calvet, L; Noblet, L; Sidhu, S; Debussche, L; Moll, J; Valtingojer, I

Tammaccaro, SL; Valtingojer, I (通讯作者)，Sanofi R&D, Oncol, F-94400 Vitry Sur Seine, France.

PHARMACEUTICALS, 2023; 16 (4):

Abstract

KRAS(G12C) is one of the most common mutations detected in non-small cell lung cancer (NSCLC) patients, and it is a marker of poor prognosis. The firs......

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