Discovery of Novel Biphenyl Carboxylic Acid Derivatives as Potent URAT1 Inhibitors

Hou, XX; Wang, YC; Yang, YJ; Xiao, ZY

Xiao, ZY (通讯作者),Chinese Acad Med Sci & Peking Union Med Coll, Inst Mat Med, Beijing Key Lab Act Subst Discovery & Druggabil Ev, Beijing 100050, Peoples R China.

MOLECULES, 2023; 28 (21):

Abstract

Urate transporter 1 (URAT1) is a clinically validated target for the treatment of hyperuricemia and gout. Due to the absence of protein structures, th......

Full Text Link