Chondrocyte mTORC1 activation stimulates miR-483-5p via HDAC4 in osteoarthritis progression

Wang, H; Zhang, HY; Sun, QY; Yang, J; Zeng, C; Ding, CH; Cai, DZ; Liu, AL; Bai, XC

Bai, XC (reprint author), Southern Med Univ, Sch Basic Med Sci, Dept Cell Biol, Guangzhou 510515, Guangdong, Peoples R China.

JOURNAL OF CELLULAR PHYSIOLOGY, 2019; 234 (3): 2730

Abstract

The hyperactivation of the mechanistic target of rapamycin complex 1 (mTORC1) in chondrocytes has been shown to accelerate the severity of destabiliza......

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