Predicting clozapine dose required to achieve a therapeutic plasma concentration - A comparison of a population algorithm and three algorithms based on gene variant models

Taylor, D; Cahill, C; Wallang, P; Millard, L; Cela, LR; Breen, KC

Taylor, D (通讯作者),Maudsley Hosp & Inst Psychiat, Pharm Dept, Denmark Hill, London SE5 8AZ, England.

JOURNAL OF PSYCHOPHARMACOLOGY, 2023; 37 (10): 1030

Abstract

Background: Clozapine is the most effective antipsychotic but requires careful titration to therapeutic blood levels. Methods to predict therapeutic d......

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