PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling

Yang, W; Yang, LF; Song, ZQ; Shah, SZA; Cui, YY; Li, CS; Zhao, HF; Gao, HL; Zhou, XM; Zhao, DM

Zhao, DM (reprint author), China Agr Univ, Natl Anim Transmissible Spongiform Encephalopathy, Coll Vet Med, Minist Agr, Beijing, Peoples R China.; Zhao, DM (reprint author), China Agr Univ, Key Lab Anim Epidemiol & Zoonosis, Coll Vet Med, Minist Agr, Beij

CNS NEUROSCIENCE & THERAPEUTICS, 2017; 23 (5): 416

Abstract

AimsThe proline-rich Akt substrate of 40-kDa (PRAS40) protein is a direct inhibitor of mTORC1 and an interactive linker between the Akt and mTOR pathw......

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