Gasdermin D membrane pores orchestrate IL-1α secretion from necrotic macrophages after NFS-rich silica exposure

Leinardi, R; Pochet, A; Uwambayinema, F; Yakoub, Y; Quesniaux, V; Ryffel, B; Broz, P; Pavan, C; Huaux, F

Leinardi, R; Pavan, C (通讯作者)，Catholic Univ Louvain, Inst Rech Expt & Clin IREC, Louvain Ctr Toxicol & Appl Pharmacol LTAP, Brussels, Belgium.;Pavan, C (通讯作者)，Univ Torino, G Scansetti Interdept Ctr Studies Asbestos & Other, Dept Chem, Turin, Italy.

ARCHIVES OF TOXICOLOGY, 2023; 97 (4): 1001

Abstract

IL-1 alpha is an intracellular danger signal (DAMP) released by macrophages contributing to the development of silica-induced lung inflammation. The e......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索