Inhibiting Histone Deacetylase as a Means to Reverse Resistance to Angiogenesis Inhibitors: Phase I Study of Abexinostat Plus Pazopanib in Advanced Solid Tumor Malignancies

Aggarwal, R; Thomas, S; Pawlowska, N; Bartelink, I; Grabowsky, J; Jahan, T; Cripps, A; Harb, A; Leng, J; Reinert, A; Mastroserio, I; Truong, TG; Ryan, CJ; Munster, PN

Munster, PN (reprint author), Univ Calif San Francisco, 1450 3rd St, San Francisco, CA 94143 USA.

JOURNAL OF CLINICAL ONCOLOGY, 2017; 35 (11): 1231

Abstract

Purpose This phase I trial evaluated epigenetic modulation of vascular endothelial growth factor (VEGF) and hypoxia-inducible factor by using a histon......

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