KRAS K104 modification affects the KRAS(G12D)-GEF interaction and mediates cell growth and motility

Chen, CC; Hsu, CY; Lin, HY; Zeng, HQ; Cheng, KH; Wu, CW; Tsai, EM; Hsieh, TH

Tsai, EM (corresponding author), Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Dept Obstet & Gynecol, Kaohsiung 807, Taiwan.; Tsai, EM (corresponding author), Kaohsiung Med Univ, Grad Inst Med, Coll Med, Kaohsiung 807, Taiwan.; Hsieh, TH (corresponding author), I Shou Univ, E Da Canc Hosp, E Da Hosp, Dept Med Res, Kaohsiung 82445, Taiwan.

SCIENTIFIC REPORTS, 2020; 10 (1):

Abstract

Mutant RAS genes play an important role in regulating tumors through lysine residue 104 to impair GEF-induced nucleotide exchange, but the regulatory ......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索