Direct Oral FXa Inhibitors Binding to Human Serum Albumin: Spectroscopic, Calorimetric, and Computational Studies

Mariño-Ocampo, N; Rodríguez, DF; Díaz, DG; Zúñiga-Núñez, D; Duarte, Y; Fuentealba, D; Zacconi, FC

Fuentealba, D; Zacconi, FC (通讯作者)，Pontificia Univ Catolica Chile, Escuela Quim, Fac Quim & Farm, Santiago 7820436, Chile.;Zacconi, FC (通讯作者)，Pontificia Univ Catolica Chile, Inst Biol & Med Engn, Sch Engn Med & Biol Sci, Santiago 7820436, Chile.;Zacconi, FC (通讯作者)，Pontificia Univ Catolica Chile, Ctr Invest Nanotecnol & Mat Avanzados, CIEN UC, Santiago 7820436, Chile.;Zacconi, FC (通讯作者)，Univ Talca, Ctr Nanomed Diag & Drug Dev ND3, Talca 3460000, Chile.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (5):

Abstract

Direct FXa inhibitors are an important class of bioactive molecules (rivaroxaban, apixaban, edoxaban, and betrixaban) applied for thromboprophylaxis i......

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