Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition

Khan, A; Valli, E; Lam, H; Scott, DA; Murray, J; Hanssen, KM; Eden, G; Gamble, LD; Pandher, R; Flemming, CL; Allan, S; Osterman, AL; Haber, M; Norris, MD; Fletcher, JI; Yu, DMT

Fletcher, JI; Yu, DMT (corresponding author), UNSW Sydney, Childrens Canc Inst, Lowy Canc Res Ctr, Sydney, NSW 2052, Australia.; Fletcher, JI; Yu, DMT (corresponding author), UNSW Sydney, Sch Womens & Childrens Hlth, Sydney, NSW 2052, Australia.

ONCOGENE, 2020; 39 (17): 3555

Abstract

Amplification of the MYCN oncogene occurs in similar to 25% of primary neuroblastomas and is the single most powerful biological marker of poor progno......

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