Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours

Tao, LW; Xiang, DX; Xie, Y; Bronson, RT; Li, Z

Li, Z (reprint author), Brigham & Womens Hosp, Dept Med, Div Genet, 75 Francis St, Boston, MA 02115 USA.; Li, Z (reprint author), Harvard Med Sch, Dept Med, Boston, MA 02115 USA.

NATURE COMMUNICATIONS, 2017; 8 ( ):

Abstract

Most breast cancers may have a luminal origin. TP53 is one of the most frequently mutated genes in breast cancers. However, how p53 deficiency contrib......

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