IL-36 in chronic inflammation and fibrosis - bridging the gap?

Elias, M; Zhao, S; Le, HT; Wang, J; Neurath, MF; Neufert, C; Fiocchi, C; Rieder, F

Rieder, F (corresponding author), Cleveland Clin Fdn, Dept Inflammat & Immun, 9500 Euclid Ave, Cleveland, OH 44195 USA.; Rieder, F (corresponding author), Cleveland Clin Fdn, Dept Gastroenterol Hepatol & Nutr, 9500 Euclid Ave, Cleveland, OH 44195 USA.

JOURNAL OF CLINICAL INVESTIGATION, 2021; 131 (2):

Abstract

IL-36 is a member of the IL-1 superfamily and consists of three agonists and one receptor antagonist (IL-36Ra). The three endogenous agonists, IL-36 a......

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