Progressive human-like tauopathy with downstream neurodegeneration and neurovascular compromise in a transgenic rat model

Emmerson, JT; Do Carmo, S; Liu, YY; Shalhoub, A; Liu, A; Bonomo, Q; Malcolm, JC; Breuillaud, L; Cuello, AC

Cuello, AC (通讯作者),McGill Univ, Dept Pharmacol & Therapeut, McIntyre Med Bldg,3655 Promenade Sir William Osler, Montreal, PQ H3G 1Y6, Canada.;Cuello, AC (通讯作者),McGill Univ, Integrated Program Neurosci, Montreal, PQ H3A 1A1, Canada.

NEUROBIOLOGY OF DISEASE, 2023; 184 ():

Abstract

Tauopathies, including frontotemporal dementia (FTD) and Alzheimer's disease (AD), clinically present with progressive cognitive decline and the depos......

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