Thrombopoietin Metabolically Primes Hematopoietic Stem Cells to Megakaryocyte-Lineage Differentiation

Nakamura-Ishizu, A; Matsumura, T; Stumpf, PS; Umemoto, T; Takizawa, H; Takihara, Y; O'Neil, A; Majeed, ABBA; MacArthur, BD; Suda, T

Nakamura-Ishizu, A; Suda, T (reprint author), Natl Univ Singapore, Canc Sci Inst, 14 Med Dr,MD6, Singapore 117599, Singapore.; Nakamura-Ishizu, A; Suda, T (reprint author), Kumamoto Univ, Int Res Ctr Med Sci, Chuo Ku, 2-2-1 Honjo, Kumamoto 8600811, Japan.

CELL REPORTS, 2018; 25 (7): 1772

Abstract

During acute myelosuppression or thrombocytopenia, bone marrow (BM) hematopoietic cells respond rapidly to replenish peripheral blood platelets. While......

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