Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody

Zhang, D; Jiang, F; Zaynagetdinov, R; Huang, H; Sood, VD; Wang, H; Zhao, XY; Jenkins, MH; Ji, QY; Wang, YB; Nannemann, DP; Musil, D; Wesolowski, J; Paoletti, A; Bartholomew, T; Derner, MG; An, Q; Iffland, C; Halle, JP

Zhang, D (corresponding author), EMD Serono Res & Dev Inst, 45 Middlesex Turnpike, Billerica, MA 01821 USA.

ONCOIMMUNOLOGY, 2020; 9 (1):

Abstract

T cell immunoglobulin and mucin domain-3 (TIM-3) is an immune checkpoint that regulates normal immune responses but can be exploited by tumor cells to......

Full Text Link