PGC-1 modulates statin-associated myotoxicity in mice

Singh, F; Zoll, J; Duthaler, U; Charles, AL; Panajatovic, MV; Laverny, G; McWilliams, TG; Metzger, D; Geny, B; Krahenbuhl, S; Bouitbir, J

Bouitbir, J (reprint author), Univ Hosp, Dept Biomed, Div Clin Pharmacol & Toxicol, Hebelstr 20, CH-4031 Basel, Switzerland.; Bouitbir, J (reprint author), SCAHT, Basel, Switzerland.

ARCHIVES OF TOXICOLOGY, 2019; 93 (2): 487

Abstract

Statins inhibit cholesterol biosynthesis and lower serum LDL-cholesterol levels. Statins are generally well tolerated, but can be associated with pote......

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