Medulloblastoma and ependymoma cells display increased levels of 5-carboxylcytosine and elevated TET1 expression

Ramsawhook, A; Lewis, L; Coyle, B; Ruzov, A

Coyle, B (reprint author), Univ Nottingham, Sch Med, Childrens Brain Tumour Res Ctr, QMC, Nottingham NG7 2UH, England.; Ruzov, A (reprint author), Univ Nottingham, Sch Med, Div Canc & Stem Cells, Ctr Biomol Sci, Univ Pk, Nottingham NG7 2RD, England.

CLINICAL EPIGENETICS, 2017; 9 ( ):

Abstract

Background: Alteration of DNA methylation (5-methylcytosine, 5mC) patterns represents one of the causes of tumorigenesis and cancer progression. Tet p......

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