Inferring the molecular and phenotypic impact of amino acid variants with MutPred2

Pejaver, V; Urresti, J; Lugo-Martinez, J; Pagel, KA; Lin, GN; Nam, HJ; Mort, M; Cooper, DN; Sebat, J; Iakoucheva, LM; Mooney, SD; Radivojac, P

Radivojac, P (corresponding author), Indiana Univ, Dept Comp Sci, Bloomington, IN 47405 USA.; Mooney, SD (corresponding author), Univ Washington, Dept Biomed Informat & Med Educ, Seattle, WA 98195 USA.; Iakoucheva, LM (corresponding author), Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA.; Radivojac, P (corresponding author), Northeastern Univ, Khoury Coll Comp Sci, Boston, MA 02115 USA.

NATURE COMMUNICATIONS, 2020; 11 (1):

Abstract

Identifying pathogenic variants and underlying functional alterations is challenging. To this end, we introduce MutPred2, a tool that improves the pri......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索