Quinacrine Inhibits ICAM-1 Transcription by Blocking DNA Binding of the NF-kappa B Subunit p65 and Sensitizes Human Lung Adenocarcinoma A549 Cells to TNF-alpha and the Fas Ligand-MedSci.cn

Quinacrine Inhibits ICAM-1 Transcription by Blocking DNA Binding of the NF-kappa B Subunit p65 and Sensitizes Human Lung Adenocarcinoma A549 Cells to TNF-alpha and the Fas Ligand

Harada, M; Morimoto, K; Kondo, T; Hiramatsu, R; Okina, Y; Muko, R; Matsuda, I; Kataoka, T

Kataoka, T (reprint author), Kyoto Inst Technol, Dept Appl Biol, Sakyo Ku, Kyoto 6068585, Japan.; Kataoka, T (reprint author), Kyoto Inst Technol, CAIRP, Sakyo Ku, Kyoto 6068585, Japan.

Abstract

Quinacrine has been used for therapeutic drugs in some clinical settings. In the present study, we demonstrated that quinacrine decreased the expressi......

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Quinacrine Inhibits ICAM-1 Transcription by Blocking DNA Binding of the NF-kappa B Subunit p65 and Sensitizes Human Lung Adenocarcinoma A549 Cells to TNF-alpha and the Fas Ligand

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