DRUG RELEASE OF NANO-HYDROXYAPATITE BIOLOGICAL SUBSTITUTE LOADED WITH ISONIAZID AND RIFAMPIN IN VITRO AND ANIMAL MODELS OF SPINAL TUBERCULOSIS

Cai, ZC; Liu, J; Ma, H; Ma, R; Chen, Z; Zhang, JQ; Liu, XY; Ge, ZH

Ge, ZH (corresponding author), Ningxia Med Univ, Dept Orthoped, Gen Hosp, Yinchuan 750000, Ningxia, Peoples R China.

ACTA POLONIAE PHARMACEUTICA, 2021; 78 (2): 227

Abstract

Spinal tuberculosis drug efficacy studies have shown that a drug's clinical efficacy mainly depends on its concentration in the target tissue. To impr......

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