Targeting the cell cycle in head and neck cancer by Chk1 inhibition: a novel concept of bimodal cell death

van Harten, AM; Buijze, M; van der Mast, R; Rooimans, MA; Martens-de Kemp, SR; Bachas, C; Brink, A; Stigter-van Walsum, M; Wolthuis, RMF; Brakenhoff, RH

Brakenhoff, RH (reprint author), Vrije Univ Amsterdam, Amsterdam UMC, Canc Ctr Amsterdam, Sect Tumor Biol,Otolaryngol Head & Neck Surg, Amsterdam, Netherlands.

ONCOGENESIS, 2019; 8 ():

Abstract

Head and neck squamous cell carcinomas (HNSCCs) coincide with poor survival rates. The lack of driver oncogenes complicates the development of targete......

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