Screening antiproliferative drug for breast cancer from bisbenzylisoquinoline alkaloid tetrandrine and fangchinoline derivatives by targeting BLM helicase

Zhang, WM; Yang, S; Liu, JH; Bao, LC; Lu, H; Li, H; Pan, WD; Jiao, YC; He, ZX; Liu, JL

Liu, JL (reprint author), Guizhou Med Univ, Basic Med Coll, Dept Immunol, 9 Beijing Rd, Guiyang 550004, Guizhou, Peoples R China.; Pan, WD (reprint author), Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, 3491 Baijin Rd, Guiyang 550014, Guizh

BMC CANCER, 2019; 19 (1):

Abstract

Background: The high expression of BLM (Bloom syndrome) helicase in tumors involves its strong association with cell expansion. Bisbenzylisoquinoline ......

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