Formulation Development of Mirtazapine Liquisolid Compacts: Optimization Using Central Composite Design

Naureen, F; Shah, Y; Shah, SI; Abbas, M; Rehman, IU; Muhammad, S; Hamdullah, H; Goh, KW; Khuda, F; Khan, A; Chan, SY; Mushtaq, M; Ming, LC

Shah, Y; Shah, SI (通讯作者),Abdul Wali Khan Univ Mardan, Dept Pharm, Mardan 23200, Pakistan.;Ming, LC (通讯作者),Univ Brunei Darussalam, PAP Rashidah Saadatul Bolkiah Inst Hlth Sci, Ga, BE-1410 Gadong, Brunei.

MOLECULES, 2022; 27 (13):

Abstract

Mirtazapine is a tetracyclic anti-depressant with poor water solubility. The aim of this study was to improve the dissolution rate of mirtazapine by d......

Full Text Link