Rogaratinib in patients with advanced cancers selected by FGFR mRNA expression: a phase 1 dose-escalation and dose-expansion study

Schuler, M; Cho, BC; Sayehli, CM; Navarro, A; Soo, RA; Richly, H; Cassier, PA; Tai, D; Penel, N; Nagoya, L; Park, SH; Schostak, M; Gajate, P; Cathomas, R; Rajagopalan, P; Grevel, J; Bender, S; Boix, O; Nogai, H; Ocker, M; Eflinghaus, P; Joerger, M

Schuler, M (reprint author), Univ Duisburg Essen, West German Canc Ctr, Dept Med Oncol, D-45122 Essen, Germany.

LANCET ONCOLOGY, 2019; 20 (10): 1454

Abstract

Background The clinical activity of fibroblast growth factor receptor (FGFR) inhibitors seems restricted to cancers harbouring rare FGFR genetic aberr......

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