The inhibition of 5-Lipoxygenase (5-LO) products leukotriene B4 (LTB4) and cysteinyl leukotrienes (cysLTs) modulates the inflammatory response and improves cutaneous wound healing

Guimaraes, FR; Sales-Campos, H; Nardini, V; da Costa, TA; Fonseca, MTC; Rodrigues, V; Sorgi, CA; da Silva, JS; Chica, JEL; Faccioli, LH; Cardoso, CRD

Cardoso, CRD (reprint author), Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Anal Clin Toxicol & Bromatol, Av Cafe S-N, BR-14040903 Ribeirao Preto, SP, Brazil.

CLINICAL IMMUNOLOGY, 2018; 190 (): 74

Abstract

To analyze the participation of the enzyme 5-lipoxygenase (5-LO) in skin repair, WT wounds were compared to those in 5-LO deficient mice (5-LO-/-), wh......

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