Pharmacological and genetic targeting of 5-lipoxygenase interrupts c-Myc oncogenic signaling and kills enzalutamide-resistant prostate cancer cells via apoptosis-MedSci.cn

Pharmacological and genetic targeting of 5-lipoxygenase interrupts c-Myc oncogenic signaling and kills enzalutamide-resistant prostate cancer cells via apoptosis

Monga, J; Subramani, D; Bharathan, A; Ghosh, J

Ghosh, J (corresponding author), Henry Ford Hlth Syst, Vattikuti Urol Inst, Detroit, MI 48202 USA.; Ghosh, J (corresponding author), Henry Ford Hlth Syst, Henry Ford Canc Inst, Detroit, MI 48202 USA.

SCIENTIFIC REPORTS, 2020; 10 (1):

Abstract

Much of the morbidity and mortality due to prostate cancer happen because of castration-resistant prostate cancer (CRPC) which invariably develops aft......

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