Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling

Wong, RW; Lingwood, CA; Ostrowski, MA; Cabral, T; Cochrane, A

Cochrane, A (reprint author), Univ Toronto, Inst Med Sci, Toronto, ON M5S 1A8, Canada.; Cochrane, A (reprint author), Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, Canada.

SCIENTIFIC REPORTS, 2018; 8 ():

Abstract

The capacity of HIV-1 to develop resistance to current drugs calls for innovative strategies to control this infection. We aimed at developing novel i......

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