Young Bone-Marrow Sca-1(+) Stem Cells Rejuvenate the Aged Heart and Improve Function after Injury through PDGFR beta-Akt pathway

Li, SH; Sun, L; Yang, L; Li, J; Shao, ZB; Du, GQ; Wu, J; Weisel, RD; Li, RK

Li, RK (reprint author), Univ Hlth Network, Toronto Gen Res Inst, Div Cardiovasc Surg, Toronto, ON, Canada.; Li, RK (reprint author), Univ Toronto, Dept Surg, Div Cardiac Surg, Toronto, ON, Canada.

Scientific Reports, 2017; 7 ( ):

Abstract

Bone marrow (BM) reconstitution with young BM cells in aged recipients restores the functionality of cardiac resident BM-derived progenitors. This stu......

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