Caspase-11 promotes renal fibrosis by stimulating IL-1 beta maturation via activating caspase-1

Miao, NJ; Xie, HY; Xu, D; Yin, JY; Wang, YZ; Wang, B; Yin, F; Zhou, ZL; Cheng, Q; Chen, PP; Zhou, L; Xue, H; Zhang, W; Wang, XX; Liu, J; Lu, LM

Liu, J; Lu, LM (reprint author), Fudan Univ, Shanghai Med Coll, Sch Basic Med Sci, Dept Physiol & Pathophysiol, Shanghai 200032, Peoples R China.

ACTA PHARMACOLOGICA SINICA, 2019; 40 (6): 790

Abstract

Caspase-11 is a key upstream modulator for activation of inflammatory response under pathological conditions. In this study, we investigated the roles......

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