Effective rational humanization of a PASylated anti-galectin-3 Fab for the sensitive PET imaging of thyroid cancer in vivo

Peplau, E; De Rose, F; Eichinger, A; Reder, S; Mittelhauser, M; Scafetta, G; Schwaiger, M; Weber, WA; Bartolazzi, A; D'Alessandria, C; Skerra, A

Skerra, A (corresponding author), Tech Univ Munich, Lehrstuhl Biol Chem, D-85354 Freising Weihenstephan, Weihenstephan, Germany.

SCIENTIFIC REPORTS, 2021; 11 (1):

Abstract

The lack of a non-invasive test for malignant thyroid nodules makes the diagnosis of thyroid cancer (TC) challenging. Human galectin-3 (hGal3) has eme......

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